Long-term Outcome of AIDS-related Primary Central Nervous System Lymphoma Treated With High Dose Methotrexate and Combined Antiretroviral Therapy

Fondation Ophtalmologique Adolphe de Rothschild51 enrolled

Overview

This study aims at describing survival rates over time (Kaplan-Meier estimator) in patients suffering from AIDS-related primary central nervous system lymphoma who were diagnosed from 1996 to 2014 and treated with infusions of high-dose methotrexate and combined antiretroviral therapy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Central Nervous System Lymphoma AIDS Related Lymphoma

Interventions

Retrospective survival analysisOTHER

Kaplan-Meier model

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * HIV infection * AIDS-related primary central nervous system lymphoma * treated with at least one infusion of methotrexate and combine antiretroviral therapy Exclusion Criteria: * prior non-Hodgkin lymphoma

Locations (1)

Fondation Ophtalmologique A. de Rotchschild

Paris, France

Outcomes

Primary Outcomes

Median duration of survival after diagnosis of lymphoma (years)

Time frame: At the time of systematic files review (jan 2014) - average follow-up 7 years

Data from ClinicalTrials.gov

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