The goal of our study was to investigate whether different methods of dressing could lower catheter-associated bloodstream infections.
The study method was experimental in design and recruited 331 medical intensive care unit patients with placement of central catheters in one regional hospital in northern Taiwan. The investigators used block randomization to assign patients to the study group or control group. In study group which included 163 participants, the investigators used aseptic coverings during dressing and in the control group which included 168 participants the process of dressing was as routine. Study period started from the first day of catheter insertion and ends with either the removal of catheter or discharge from intensive care unit. The investigators defined the infection outcome according to culture results, and the guidelines by Infectious Diseases Society of America and Centers for Disease Control and Prevention, USA. Analysis was done by SPSS version 23. The investigators used percentage and average to study characteristics of participants. The investigators used Chi-Square or Fisher's exact test and Poisson distribution to analyze the incidence rate of bloodstream infections and the infection density. The investigators used Kaplan-Meier curve to demonstrate the catheter infection-free days and the catheter redness symptoms days of the two groups. The investigators used logistic regression model to analyze factors associated with development of bloodstream infections.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE
Enrollment
331
Replacement of the central venous catheters in the dressing process
Catheter-related blood stream infections density after dressing change
Confirm blood culture results and judge whether it is catheter related Bloodstream infection(CRBSI)
Time frame: up to 18 months
Central Line-Associated Bloodstream Infection density after dressing change
Confirm blood culture results and judge whether it is catheter related Bloodstream infection, CLABSI
Time frame: up to 18 months
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