patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate while the intervention one will have coronally advanced flap with advanced platelet rich fibrin(A-PRF).as it represent a new generation of platelet concentrate allow for better healing and root coverage results. Null hypothesis: In patients with Miller class I and II gingival recession, there is no difference in amount of root coverage (mm) following the application of SCTG+A-PRF compared to CAF+SCTG.
* Population (P): Patients with single Miller class I, II gingival recessions. * Intervention (I): Coronally advanced flap (CAF) plus platelet rich fibrin (A-PRF). * Comparator (C): Coronally advanced flap (CAF) plus subepithelial connective tissue graft (SCTG). * Primary Outcome (O): Root coverage (mm). * Time frame: 9 months. * Study design: Randomized controlled clinical trial. * Patients are to be selected from the outpatient clinic of the department of Oral Medicine and Periodontology-Cairo University
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
20
advanced platelet rich fibrin prepared by low speed centrfugation concept(LSCC) together with coronally advanced flap .
cornally advanced flap plus subepithilial connective tissue graft harvested from the palate
root coverage
measured in millimeter
Time frame: 9 months
Gingival esthetics
Root coverage esthetic score
Time frame: 9 months
Recession width
measured in millimeter
Time frame: 9 months
Clinical attachment level
measured in millimeter
Time frame: 9 months
Width of keratinized gingiva
measured in millimeter
Time frame: 9 months
Probing depth
measured in millimeter
Time frame: 9 months
Gingival thickness
measured in millimeter
Time frame: 9 months
Post-operative pain
Visual analog scale (VAS) Questionnaire
Time frame: measured daily for the first 2 weeks post- operatively.
Patient Satisfaction
Post-Surgical Patient Satisfaction Questionnaire
Time frame: 9 months
Early wound healing
Early wound healing index
Time frame: 1,2,4 weeks post- surgical
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