Determination of the Utility of Pfizer's Pneumococcal Urine Antigen Test in Children 5 Years of Age or Younger With Community Acquired Pneumonia in Guatemala

CASES: Inclusion Criteria: * Age older than 1 month (31 days) and up to 71 months and 28 days. * Diagnosis of radiologically confirmed pneumonia per WHO criteria in the ED or hospital within 48 hours of hospital admission * Signed informed consent by parents or legal guardian to participate in the study Exclusion Criteria: * Known immunodeficiency * Major congenital malformation (e.g., hemodynamically compromised congenital heart malformation or any malformation leading to recurrent pneumonia) or serious chronic disorder * Significant neurological disorder * Hospitalization within the previous 30 days for pneumonia or respiratory infection * Use of parenteral antibiotics for current illness (leading to diagnosis of pneumonia) * Transferred to the study hospital after already being hospitalized at a different location for ≥ 48 hours CONTROLS: Inclusion Criteria: * Age 1 to 71 months and signed informed consent by parents or legal guardian Exclusion Criteria: * Known immunodeficiency * Major congenital malformation (e.g., hemodynamically compromised congenital heart malformation or any malformation leading to recurrent pneumonia) or serious chronic disorder * Significant neurological disorder * Fever or suspicion of community-acquired pneumonia or other respiratory infectious disease (symptoms of cough, congestion, tachypnea, indrawing, etc.) * Hospitalization within the previous 30 days for pneumonia or respiratory infection