The main objective of this study is to evaluate the effects of tRNS while undergoing computerized cognitive rehabilitation therapy to conclude if this combination of therapies would be effective for the cognitive rehabilitation of patients with acquired brain damage, such as traumatic brain injury. We want to study the therapeutic potential of tRNS to enhance the therapeutic outcome of cognitive training, studying its global effect over the rehabilitation of attention, memory and executive functions, compared to sham tRNS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
30
The treatment consists of a set of 1-h sessions, three sessions per week for 8 weeks. A series of cognitive exercises of attention, memory, and executive functions will be conducted in each session. During the first 20 minutes of each cognitive training session, patients will receive bi-frontal and bi-parietal tRNS. It has a start and end ramp of two seconds in each case to avoid the slight unpleasant sensation that occurs in the first moments of the introduction of direct current DC.
The treatment consists of a set of 1-h sessions, three sessions per week for 8 weeks. A series of cognitive exercises of attention, memory, and executive functions will be conducted in each session. We will apply a sham tRNS for the first 20 minutes of each cognitive training session. The subjects will receive sham tRNS and will perform the same type of cognitive training as the rest of patients and will receive the same type of adverse reaction questionnaire. Subjects receiving simulated stimulation will receive the same type of ramps at the beginning and end of the session to ensure triple-blind maintenance .
Institut Guttmann
Badalona, Barcelona, Spain
RECRUITINGConners Continuous Performance Test (CPT-II)
To improve performance in sustained attention after receiving experimental intervention.
Time frame: 1 day
Digit Span Forward from the Wechsler Adult Intelligence Scale
To improve performance in span of immediate verbal recall after receiving experimental intervention.
Time frame: 1 day
Digit Span Backward from the Wechsler Adult Intelligence Scale
To improve performance in working memory after receiving experimental intervention.
Time frame: 1 day
Rey Auditory Verbal Learning Test
To improve performance in short-term, long-term and recognition.
Time frame: 1 day
Letters and Numbers from the Wechsler Adult Intelligence Scale
To improve performance in working memory after receiving experimental intervention.
Time frame: 1 day
Spanish phonemic fluency test (PMR)
To improve performance in phonemic fluency after receiving experimental intervention.
Time frame: 1 day
Trail Making Test A (TMT-A)
To improve performance in visual attention
Time frame: 1 day
Trail Making Test B (TMT-B)
To improve performance in task-switching
Time frame: 1 day
Wisconsin Card Sorting Test (WCST)
To improve performance in set-shifting
Time frame: 1 day
Stroop Color and Word test (Stroop Test)
To improve performance in inhibitory control
Time frame: 1 day
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