A Safety and PK Study of IV Eravacycline

Inclusion Criteria: 1. Male or female from 8 to \<18 years of age on the day informed consent (and assent, if applicable) is obtained 2. Written informed consent from parent(s) or other legally authorized representative(s) and informed assent from subject (if age appropriate according to local requirements) 3. Hospitalized, in stable condition, and receiving or plan to receive within 24 hours systemic antibiotic therapy, other than eravacycline, for a suspected or confirmed bacterial infection 4. Likely to survive the current illness 5. In the Investigator's opinion, the subject will require hospitalization for at least 24 hours following administration of the study drug 6. The subject appears to have sufficient intravascular access (peripheral or central) to receive study drug Exclusion Criteria: 1. Evidence or history of a clinically significant medical condition that may, in the assessment of the Investigator, impair study participation or pose a significant safety risk or diminish the subject's ability to undergo all study procedures and assessments 2. Received an investigational product and/or device within 30 days prior to study drug administration or is currently enrolled in any other clinical study involving an investigational product or any other type of medical treatment judged by the Investigator, in consultation with the Medical Monitor, not to be scientifically or medically compatible with this study 3. History of hypersensitivity to tetracycline antibiotics 4. Prior dosing in this protocol 5. Unlikely to survive at least 48 hours following administration of study drug 6. Unable or unwilling, in the judgment of the Investigator, to comply with the protocol 7. Subject is a child of an employee of the Investigator or study center who has direct involvement in the proposed study or other studies under the direction of the same Investigator or study center, or an immediate family member of the employee or the Investigator, defined as a spouse, parent, child, or sibling, whether biological or legally adopted 8. Breastfeeding females 9. Females of childbearing potential \[those with menarche and/or thelarche (beginning of breast development)\] and sexually active males who are unwilling or unable to use an acceptable method of contraception 10. Positive pregnancy test in females of childbearing potential 11. Any other circumstance that, in the opinion of the Investigator, would preclude subject participation in the study