To assess the two-week ocular responses, especially on pupillary size and accommodative amplitude, of nightly application of 0.01% or 0.02% or 0.03% atropine eye drops in children with myopia who were randomized to use of three different low-concentration atropine eye drops
Atropine was proven to be effective in controlling myopia progression. However, the most common side effects of the use of atropine eye drop are dilation of pupil and decrease of accommodation. The investigators wish to evaluate the ocular responses of three low concentration atropine eye drops, 0.01% or 0.02% or 0.03%, mainly on the pupillary size and accommodative responses in children aged between 6 to 12 years old over two-week usage.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Enrollment
58
0.01% atropine sulphate
0.02% atropine sulphate
0.03% atropine sulphate
Department of Ophthalmology - An Sinh Hospital
Ho Chi Minh City, Vietnam
Change in pupillary diameter
Measure and compare the photopic and mesopic pupil size (milimeters) before and after instillation of eye drops
Time frame: at baseline, at three day and at two week
Change in accommodative amplitude
Measure and compare the accommodative amplitude (diopters) before and after instillation of eye drops
Time frame: at baseline, at three day and at two week
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