Mycological Comparative Study on Maxillary Dentures of Two Different Materials

Ali ibrahim mahmoud shamardal34 enrolled

Overview

Cross over design the investigator divide participants to two groups group (A) will receive rapid heat cured denture base material and group (b) will receive the acrylic denture modified by titanium dioxide nanoparticles and after washout period alternatively group (a) will receive the acrylic denture modified by titanium dioxide nanoparticles AND group (b) will receive rapid heat cured denture base material the investigator will take swaps from dentures to count the candida species

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Effect of Tio2 Nanoparticles on Candida Aggregation

Interventions

titanium dioxide dentureOTHER

patients will receive titanium dioxide denture (made from acrylic resin with titanium dioxide nanoparticles ) for 1 month in the initial phase then in the second phase after one month they will receive( rapid heat cured acrylic resin)denture according to the principle of crossover des

Eligibility

Sex: ALLMin age: 30 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Completely edentulous maxillary arch and partially dentate mandibular arch with adequate interarch space. * The edentulous ridges should be covered by firm healthy mucosa. * Angle class I maxillomandibular relation. * Healthy and cooperative patient Exclusion Criteria: * Patients with bad habits as severe clenching or bruxism, drug or alcohol addiction, moderate or heavy smoking (greater than 10 cigarettes per day). * Previous history of radiotherapy or chemotherapy. * Any skeletal problem dictates surgical intervention

Outcomes

Primary Outcomes

Mycological investigation

Count of candida on the fitting surface of denture by (CFU) unit

Time frame: 6 months

Data from ClinicalTrials.gov

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