The purpose of this study is to determine the effectiveness of relatlimab plus nivolumab, alone or in combination with various standard-of-care treatments in participants with gastric cancer (GC) or gastroesophageal junction (GEJ) adenocarcinoma that has come back or spread to other places in the body after prior therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Overall response rate (ORR)
Time frame: Approximately 31 months
Incidence of adverse events (AEs)
Time frame: Approximately 5 years
Incidence of serious adverse events (SAEs)
Time frame: Approximately 5 years
Incidence of AEs leading to discontinuation
Time frame: Approximately 5 years
Incidence of deaths
Time frame: Approximately 5 years
Incidence of laboratory abnormalities
Time frame: Approximately 5 years
ORR
Cohort A1
Time frame: Approximately 5 years
Duration of response (DOR)
Time frame: Approximately 5 years
Progression free survival (PFS)
Time frame: Approximately 5 years
Overall survival (OS)
Time frame: Approximately 5 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Specified dose on specified days
Local Institution
Daphne, Alabama, United States
Local Institution
Bakersfield, California, United States
Local Institution
Fullerton, California, United States
Local Institution
Los Angeles, California, United States
Local Institution
Redondo Beach, California, United States
Local Institution
Santa Barbara, California, United States
Local Institution
Aurora, Colorado, United States
Local Institution
Lakewood, Colorado, United States
Local Institution
Miami, Florida, United States
Local Institution
Tampa, Florida, United States
...and 74 more locations