Evaluation of the Renal Congestion, Perfusion and Function Before and After Diuretic Treatment in the ICU

University Hospital, Strasbourg, France120 enrolled

Overview

Renal congestion is a pathological state that can lead to acute kidney failure. Furosemide is known to lower renal congestion by its diuretic effect. The aim of this trial is to study the reversibility of kidney congestion under diuretic therapy and assess through echodoppler parameters if it can improve renal perfusion and function in congestive ICU patients. It could in fine lead to a better identification of patients that could benefit from diuretic therapy in the ICU.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Renal Congestion

Interventions

non applicableOTHER

non applicable

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patient hospitalized in ICU * under furosemide treatment Exclusion Criteria: * participation refusal * uncontrolled shock (MAP\<65mmHg) * abdominal compartment syndrome * diuretic administration in the 6 hours prior to inclusion * renal replacement therapy or stage 4-5 chronic kidney disease * atrial fibrillation * no monitoring of CVP / invasive arterial pressure

Locations (3)

CHU Amiens-Picardie

Amiens, France

NOT_YET_RECRUITING

CHU de Dijon

Dijon, France

NOT_YET_RECRUITING

Les Hôpitaux Universitaires de Strasbourg

Strasbourg, France

RECRUITING

Outcomes

Primary Outcomes

Effects of diuretics

Evaluation of renal perfusion diuretic treatment by measuring the renal resistance index and the renal venous impedance index.

Time frame: 24 hours

Data from ClinicalTrials.gov

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