Efficacy of Psychotherapy for Improving Quality of Life in Patients With Hypertrophic Cardiomyopathy and Depression

Xijing Hospital100 enrolled

Overview

A Study to evaluate the efficacy of psychotherapy for easing the cardiac symptoms and improving and quality of life in patients with hypertrophic cardiomyopathy accompanied with depression

This study will use a 8 week parallel group design. 100 patients diagnosed as hypertrophic cardiomyopathy accompanied with depression will be into experimental group and control group. The experimental group received 8 times of psychological treatments for once each week; the control group did not receive any antidepressant treatment. Follow-up assessments will be performed at baseline, week 4 and 8.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Hypertrophic Cardiomyopathy Depression Anxiety Psychotherapy

Interventions

PsychotherapyOTHER

Psychotherapy has gained increasing acceptance as a major treatment option for mood disorders.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed as hypertrophic cardiomyopathy; * Diagnosed as depression; Exclusion Criteria: * Patients with left ventricular ejection fraction (EF) ≦ 30%; * Renal dysfunction with serum creatinine ≧451umol/l; * Severe heart failure and New York Heart Association (NYHA) Heart Failure Grade III; * Combine with any type of malignant tumor; * Combine with other serious mental illnesses such as bipolar disorder, schizophrenia, schizophrenia-like illness, severe dementia, etc.; * Have received medication of antidepressant or psychotherapy; * Patients with major depression; Patients with a serious risk of suicide or have had suicide attempts; * Pregnant women and lactating women, or women who are planning to become pregnant or breastfeeding during the study period; * Other circumstances in which the researcher judges that it is not suitable as a research object.

Outcomes

Primary Outcomes

Changes in The Quality of Life, Enjoyment and Satisfaction Questionnaire (Q-LES-Q) score between groups over time

The Quality of Life, Enjoyment and Satisfaction Questionnaire (Q-LES-Q) tests the quality of life and gives emphasis to the subjective perspective of patients on physical, psychological and social domains.