Identify the unique associations of body shape to body composition and bone density indices in a pediatric population that represents the variance of sex, age, BMI-Z, and ethnicity found in the US population. Describe the precision and accuracy of optical scans to monitor change in body composition, bone density and metabolic health interventions. Estimate the level of association of optical to common health indicators including metabolic risk factors (glucose, triglycerides, HDL-cholesterol, blood pressure, VAT, WC and strength) by gender, race, age, and BMI-Z. Investigate holistic, high-resolution descriptors of 3D body shape as direct predictors of body composition and metabolic risk using statistical shape models and Latent Class Analysis.
Study Type
OBSERVATIONAL
Enrollment
430
University of California, San Francisco
San Francisco, California, United States
University of Hawaii Cancer Center
Honolulu, Hawaii, United States
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States
Fat mass by DXA
Measure fat mass and percent fat (arms, legs, trunk, and total) using Dual energy X-ray absorptiometry (DXA) data
Time frame: 1 day
Lean mass by DXA
Measure lean mass (arms, legs, trunk, and total) using Dual energy X-ray absorptiometry (DXA) data
Time frame: 1 day
Bone mass by DXA
Measure bone mass (arms, legs, lumbar spine, and total) and Bone Mineral Density (spine and total) using Dual energy X-ray absorptiometry (DXA) data
Time frame: 1 day
Fat mass by MRI
Measure fat mass and percent fat (arms, legs, trunk, visceral, and total) using MRI data
Time frame: 1 day
Lean mass by MRI
Measure lean mass (arms, legs, trunk, and total) using MRI data
Time frame: 1 day
Waist to Hip ratio (WHR) from manual tape measurement
Manual physical anthropometry of waist and hip circumferences
Time frame: 1 day
Automatic 3D optical (3DO) scan measurement
Automated 3DO measurement generated across the body
Time frame: 1 day
Hand-grip strength
Measured by using a hand-grip dynamometer (JAMAR) as a measure of strength and physical capacity.
Time frame: 1 day
Isokinetic peak torque
Measure the peak torque value (FT-LBS) generated during isokinetic knee extension/flexion movement evaluation at 60 degrees will be assessed with the HUMAC NORM device
Time frame: 1 day
Isometric peak torque
Measure the peak torque value (FT-LBS) generated during isometric knee extension/flexion movement evaluation at 60 degrees will be assessed with the HUMAC NORM device
Time frame: 1 day
Fasting glucose levels
Measure fasting glucose levels
Time frame: 1 day
Fasting HbA1c levels
Measure fasting HbA1c levels
Time frame: 1 day
Fasting insulin levels
Measure fasting insulin levels
Time frame: 1 day
Fasting cholesterol levels
Measure fasting cholesterol levels
Time frame: 1 day
Fasting triglycerides levels
Measure fasting triglycerides levels
Time frame: 1 day
Fat loss
Measure changes in fat mass during intervention using DXA data.
Time frame: 24 weeks
Changes in lean mass
Measure changes in lean mass (arms, legs, trunk, and total) during intervention using DXA data.
Time frame: 24 weeks
Changes in WHR
Measure changes in WHR during intervention
Time frame: 24 weeks
Changes in automatic 3DO scan measurement
Changes of automated 3DO measurements during intervention
Time frame: 24 weeks
Changes in isokinetic peak torque
Measure the change in peak torque value generated during isokinetic knee extension/flexion movement evaluation at 60 degrees will be assessed with the HUMAC NORM device pre and post intervention.
Time frame: 24 weeks
Changes in isometric peak torque
Measure the change in peak torque value generated during isometric knee extension/flexion movement evaluation at 60 degrees will be assessed with the HUMAC NORM device pre and post intervention
Time frame: 24 weeks
Total Body Water
Measure total body water (L) provided by bioelectrical impedance analysis
Time frame: 24 weeks
Phase angle
Phase angle \[PhA(°) = (reactance/electrical resistance) × (180°/Π)\] will be measured in degrees using bioelectrical impedance analysis.
Time frame: 24 weeks
Percent body fat
Measure percent body fat provided by bioelectrical impedance analysis.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: 24 weeks
Body circumference from 2D imaging
A conventional digital camera will be used to capture 2D images of participants in a standardized pose. Body circumference will be estimated using these images.
Time frame: 24 weeks
Systolic and Diastolic blood pressure levels will be assessed
Manually measure systolic and diastolic blood pressure levels.
Time frame: 24 weeks
Diet History Questionnaire II
The Diet History Questionnaire II estimates the participants nutrition intake by asking the participant a series of questions
Time frame: 24 weeks