The purpose of this study is to assess an effective single oral supplement or combination of oral supplements for increasing whole blood NAD+ levels.
This is a open-label dose finding study to detect an effective single oral supplement or combination of oral supplements for enhancing whole blood levels of NAD+. Each subject will receive a specific dose of the formulation once daily for 3 days followed by a washout period. Upon completion of the treatment phase, there is a post-treatment period of assessments. Participants receive assessments of blood tests, vital signs, body weight with completion of questionnaires. The primary objective of the study is to identify the ideal dosage of an oral supplement to increase whole blood NAD+ levels in adults. The secondary objective of the study is to monitor for safety from a change in fasting blood chemistry panel parameters after three day's dosing compared to cycle baseline.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
8
1, 2 or 4 capsules daily of oral supplement A for 3 days
4 capsules daily of oral supplement B for 3 days
1,2 or 4 capsules daily of oral supplement C for 3 days
Life Extension Clinical Research, Inc.
Fort Lauderdale, Florida, United States
Assess the mean change in NAD+ levels from baseline
Mean change in NAD+ levels
Time frame: 63 days
Assess the mean change in AST (aspartate aminotransferase) levels from baseline
Mean change in AST level
Time frame: 63 days
Assess the mean change in ALT (alanine aminotransferase) levels from baseline
Mean change in ALT level
Time frame: 63 days
Assess the mean change in Total Cholesterol levels from baseline
Mean change in Total Cholesterol level
Time frame: 63 days
Assess the mean change in Triglycerides levels from baseline
Mean change in Triglycerides level
Time frame: 63 days
Assess the mean change in LDL Cholesterol levels from baseline
Mean change in LDL Cholesterol level
Time frame: 63 days
Assess the mean change in HDL Cholesterol levels from baseline
Mean change in HDL Cholesterol level
Time frame: 63 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
1 or 2 tablets daily of oral supplement D for 3 days
1 or 2 tablets of oral supplement D in combination with 2 or 4 capsules of oral supplement C for 3 days