Single Nucleotide Polymorphisms (SNPs) Associated With Postherpetic Neuralgia

Second Affiliated Hospital, School of Medicine, Zhejiang University181 enrolled

Overview

Postherpetic neuralgia (PHN) is a common condition and affecting 5 to 30% of the herpes zoster patients. In some cases, the pain remained refractory after first and second line treatment for herpes zoster. This suggests that there may be genetic variants that make some patients susceptible to PHN. Using saliva samples from herpes zoster patients the investigators are going to analyze the relationship between single nucleotide polymorphisms (SNPs) in genes that are known to be involved in pain and PHN.

Study Type

OBSERVATIONAL

Enrollment

181

Conditions

Postherpetic Neuralgia

Eligibility

Sex: ALLMin age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age more than 50 years * Clinically defined herpes zoster patients Exclusion Criteria: * Patients not able to provide informed consent

Locations (1)

The second affiliated hospital of Zhejiang University

Hangzhou, Zhejiang, China

Outcomes

Primary Outcomes

correlation between pain SNPs and PHN

Time frame: At Enrollment

Data from ClinicalTrials.gov

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