NCT03710577 - Endocannabinoid and Psychological Responses to Yoga in Healthy Adults | Crick | Crick

Endocannabinoid and Psychological Responses to Yoga in Healthy Adults

N/ACompletedNCT03710577

University of Wisconsin, Madison12 enrolled

Overview

This study evaluates the acute effect of yoga on plasma levels of endocannabinoids and mood (i.e., mood disturbance, anxiety, pain) compared to one session of quiet rest. Participants completed one session of yoga and one session of quiet rest on two separate days.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

12

Conditions

Interventions

YogaBEHAVIORAL

1 session

Quiet RestBEHAVIORAL

1 session

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * greater than or equal to 18 years old and \< 45 years old and * report being healthy. Exclusion Criteria: * Being pregnant or planning to become pregnant, * currently smoking, * having a history of light headedness or fainting during blood draws or physical activity, * having a history of chest pain during physical activity, * having a bone, joint, cardiac, or other medical condition that a doctor has said may be worsened by physical activity, * taking medications for any chronic diseases such as high blood pressure or diabetes, * responding 'Yes' to any of the seven questions on the Par-Q.

Locations (1)

University of Wisconsin-Madison Natatorium

Madison, Wisconsin, United States

Outcomes

Primary Outcomes

Change in Plasma Concentration of N-arachidonoylethanolamine

Plasma concentration of anandamide, one effector of the endocannabinoid system

Time frame: This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

Change in Plasma Concentration of 2-Arachidonoylglycerol (2-AG)

Plasma concentration of 2-AG, one effector of the endocannabinoid system

Time frame: This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

Secondary Outcomes

Change in Total Mood Disturbance as Measured by the Profile of Mood States

65-item self-reported mood questionnaire that measures mood "right now." Scores range from 0-200 with higher scores indicating higher mood disturbance.

Time frame: This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

Change in State Anxiety as Measured by the State-Trait Anxiety Inventory

20-item self-reported anxiety questionnaire that measures anxiety "right now." Scores range from 20-80 with higher scores indicating higher anxiety.

Time frame: This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

Change in Total Pain as Measured by the Short-form McGill Pain Questionnaire

15-item self-reported pain questionnaire that measures pain "right now." Scores range from 0-45 with higher scores indicating higher pain.

Time frame: This will be measured 2 times during each study visit, once before the assigned study task (i.e., baseline) and once upon task completion (i.e., approx. 40 min. later)

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.