This multicenter, prospective randomized controlled study is designed to applicate perioperative Enhanced recovery after surgery (ERAS) management for children with acute complicated appendicitis, the aim is to promote postoperative recovery, shorten the hospital length of stay, and reduce the incidence of postoperative complications.
The purpose of this study is through multi-center prospective RCT research, to discuss the application of ERAS in children with acute complicated appendicitis, including its preoperative rehydration, postoperative analgesia, preoperative and postoperative antibiotics application, as well as the discharge standards and so on. The major outcome is whether it can reduce the length of stay in hospital (LOS), secondary outcomes are included the incidence of postoperative complications and postoperative readmission rate, etc.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
893
1. preoperative pain control; 2. avoiding application of ureter; 3. avoiding application of gastric tube; 4. avoiding application of irrigation; 5. avoiding application of drainage; 6. early exercising postoperatively; 7. early oral feeding postoperatively; 8. early discharging.
Tongji Hospital
Wuhan, Hubei, China
length of stay
less hospital length of stay
Time frame: through study completion, an average of 7 days
first time for postoperative feeding
earlier postoperative feeding
Time frame: up to 72 hours
first time for postoperative exercising
earlier postoperative exercising
Time frame: 1-2 days
rate of postoperative complication
less postoperative complication
Time frame: 1 months
rate of re-operation
less rate of re-operation
Time frame: 1 months
rate of re-admission
less rate of re-admission
Time frame: 1 months
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