Programmed Intermittent Epidural Bolus For Laboring Obstetrical Women

University of British Columbia390 enrolled

Overview

Comparison of three programmed intermittent epidural bolus (PIEB) pump settings for maintenance of labour analgesia.

The optimal PIEB and patient controlled epidural administered (PCEA) bolus settings are still unknown. Therefore, in this study, the investigators aim to compare analgesia outcomes both high and low PIEB flow rate settings.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

390

Conditions

Labor Pain

Interventions

Bupivacaine 0.08% - fentanyl 2mcgDRUG

In each arm, bupivacaine and fentanyl are being delivered at different intervals and rates for the maintenance of labor analgesia.

Eligibility

Sex: FEMALEMin age: 19 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Singleton, vertex presentations at term (37-42 weeks gestational age) * \</= 5cm cervical dilation at the time of epidural anesthesia request * ASA 2-3 patients aged 19 or over who are able to provide informed consent Exclusion Criteria: * Contraindications to neuraxial analgesia or risk factors likely to affect placement or function of the epidural * History of hypersensitivity or idiosyncratic reaction to local anesthetics or opioids * Current or historical evidence of any significant medical conditions * Clinical settings in which continuous epidural infusion may be preferable * Risk factors significantly increasing the need for Cesarean delivery * Anticipated fetal abnormalities

Locations (1)

BC Women's Hospital

Vancouver, British Columbia, Canada

Outcomes

Primary Outcomes

Breakthrough pain

Proportion of patients in each group who required a provider administered supplemental bolus for breakthrough pain

Time frame: Duration of labor with epidural

Data from ClinicalTrials.gov

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