Clinical Trial for Measles - Rubella Combined Vaccine (MRVAC) Produced by POLYVAC (Phase III)

Inclusion Criteria: * For children 1-2 years old: All subjects must meet all of the following criteria at the time of enroll to stduy: * Healthy children from 1 year to 2 years old. * Full-term birth: Pregnancy ≥ 37 weeks. * Weight at birth is at least 2.5kg. * Do not get any disease through a clinical examination and ask for medical history before taking part in the study (according to the prescribed information). * Have not injected Rubella vaccine or a combination vaccine containing Rubella vaccine. * Have not infected by Rubella before. * Parents or legal guardians agree to voluntarily consent to their child's participation in the study. Parent or legal guardian is provided basic information about the vaccine as well as benefits, obligations and meaning of participating in the trial. There must be a written consent form for your child to participate. * For people from 1 year to 45 years old: * Do not get any disease through a clinical examination and ask for medical history before taking part in the study (according to the prescribed card). * Have not infected by Rubella before. * For people over 2 years old up to 18 years old: Parents or legal guardians agree to voluntarily consent to their child's participation in the study. Parent or legal guardian is provided basic information about the vaccine as well as benefits, obligations and meaning of participating in the trial. There must be a written consent form for your child to participate. * For people aged 18 to 45: Completely volunteering to participate in the study after having been provided with basic information about the trial vaccine as well as the benefits, obligations and meaning of the trial participation. Must sign in the consent form to participate in the study. Exclusion Criteria: * Fever within 3 days before vaccination (body temperature ≥ 38 degrees Celsius) Persons with congenital malformations, neurological disorders, psychiatric disorders or families with neurological or psychiatric conditions or brain damage. * Having abnormal immune status or being treated for immunological control; Being immunocompromised as a result of progressive disease treatment. * Have received immunosuppressive drugs (steroid group) for more than 2 weeks before starting the vaccination. * Allergy to any vaccine component including hypersensitivity reactions and anaphylactic shock to the antibiotics (Kanamycine and Erythromycin), egg products and gelatin. * Family history of immunodeficiency. * Have a history of high fever, seizures * premature birth (\<37 weeks) (applicable to children 1-2 years). * Malnutrition level 3 or above (applicable to children 1-2 years). * Have used of gamma globulin, blood transfusions within 3 months before vaccination or gamma glubolin in large doses or the use of immunosuppressive drugs within 6 months before vaccination * Have used live vaccines within 27 days before vaccination; Have used other vaccines within 4 weeks before entry to study; Use of immunoglobulins or blood products within 3 months before vaccination; * Is participating in trial other drugs or vaccines; Has an acute or chronic disease that affects the safety (including but not limited to: chronic liver disease, some kidney disease, progressive or unstable neurological disorders, diabetes and organ transplants). * Having serious acute illness. Responsible doctor or doctor in charge of evaluation consider as unsuitable, such as having abnormal crying ... * Having plan to go far from the study site between visits. - Being pregnant (for women aged 14 - 45 years) * Trial subjects must satisfy selection criteria and not be subjected to exclusion criteria.