The aim of this study is to look at the effect Sunfiber has on the gut microbiota.
This is a randomized, double-blind, placebo-controlled crossover study with a 2 week washout period. Healthy volunteers will receive placebo, 4 grams, or 8 grams of Sunfiber in addition to their regular diet. Fecal samples will be collected for measurement of bowl function, including the gut microbiota.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
30
Partially hydrolyzed guar gum (PHGG) commercially available as Sunfiber in 3 gram doses
Participants will receive the placebo/dextrose.
Partially hydrolyzed guar gum (PHGG) commercially available as Sunfiber in 6 gram doses
Department of Food Science and Nutrition
Saint Paul, Minnesota, United States
Analysis of Microbiota
Bacterial phyla, genera, and species of bacteria will be detected using real tijme PCR. All abundances will be calculated and presented as relative levels (relative to the total amount of eubacteriausing a universal eubacteria prijer set)
Time frame: Day 10
salivary cortisol
Salivary cortisol will be measured using a competitive immunoassay. 25 ul of saliva will be used in each replicate and results will be compared to a standard curve and calculated as ug/dl.
Time frame: Day 10
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