Burn patients meeting inclusion criteria will receive the esterified hyaluronic acid matrix as the matrix for their wound, in conjunction with the standard of care for managing these types of wounds. The study will be divided into two phases. Phase I will entail intervention with the wound matrix and will continue until one of the following occur, sufficient granulation has occurred and the patient can receive a STSG and proceed to Phase II, the patient's physician determines an STSG is no longer necessary or two applications with the wound matrix occur and no STSG is approved. Phase II will begin following the STSG procedure. In this phase, the wound will be monitored and proportion of STSG take will be evaluated but no application of the wound matrix device will take place. This phase will continue for 28 days or if the physician deems the patient no longer needs regular care to monitor the wound, whichever occurs earlier.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
5
A non-woven pad composed of esterified hyaluronic acid, covered with a semipermeable silicone layer to protect the wound and control water vapor loss
Number of Days From Initial Application of Wound Matrix to Approval of Wound to Receive a Split Thickness Skin Graft
Time frame: Baseline to 42 days
Change in Wound Volume From the Time Prior to Application of the Wound Device to the Time Before the Application of STSG and After STSG
Time frame: Baseline to 42 days
Length of Stay in Inpatient Unit
Time frame: Baseline to 42 days
Patient Pain Rating
Time frame: Baseline to 42 days
Proportion of Split Thickness Skin Graft Take for the Wound at 28 Days
Time frame: 28 days
Proportion of Patients Who Develop an Infection of the Target Wound at Any Time Per Confirmation With Culture
Time frame: Baseline to 70 days
Subject Discharge Destination
The facility that the subject is discharged to will be captured.
Time frame: Baseline to 70 days
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