An Evaluation of a Collagen Dressing to Treat Chronic, Stalled Lower-extremity Wounds

Inclusion Criteria: * Has one of the following types of wounds below the knee: diabetic ulcers, pressure ulcers, venous ulcers, ulcers of mixed-vascular origin, traumatic wounds, or post-surgical wounds * Wound has been present for at least four weeks * Wound is free of necrotic tissue or debridement practices will take place prior to initial visit in order to remove necrotic tissue * Wound has failed at least one wound care treatment * Wound size is between 1 and 100 square centimeters * Patient has adequate circulation as demonstrated by biphasic or triphasic Doppler waveform, measured within three months prior to study enrollment. If monophasic on exam, then non-invasive tests must display Ankle Brachial Index greater than 0.8 and no worse than mild disease on segmental pressures. * Wound is confirmed as being free of infection and absence of osteomyelitis Exclusion Criteria: * Pregnant, planning to become pregnant during the study timeframe, or breast feeding * Unable or unwilling to receive porcine collagen * Wound is infected or presence of osteomyelitis * Allergy or sensitivity to collagen * Inability, in the opinion of the Investigator to follow protocol requirements, attend follow up visits in a timely manner, or otherwise comply with the requirements of the protocol