In this trial - the investigators plan to study the efficacy of pregnancy management in cases of suspcted preeclampsia, based on a 6-hour urine collection for protein, as compared to the standard 24-hour collection. For participants hospitalized at the maternal fetal unit at our institution, one sample of urine collected over 6 hours will be analyzed, and a second one following an additional 18 hours. Participants will be blinded to the urine collection result used to manage their pregnancy (actual 24 hour collection versus calculated 24-hour collection), as will be their attending physicians. An external physician will compare the two urine collection results, and in case only one is pathological (\>300 mg), will notify the research team and the attending physician.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Enrollment
100
This intervention includes the analysis of a 6-hour urine collection for protein, to serve for a calculated 24-hour result, according to which pregnancy will be managed.
Edith Wolfson Medical Center
Holon, Israel
Number of participants with an adverse maternal outcome composite
Defined as one of the following maternal complications - hepatic or renal injury, placental abruption, eclampsia, thrombocytopenia, cerebral morbidity, respiratory morbidity, blood pressure \> 160/110, need for anti-hypertensives
Time frame: Up to 18 weeks
Number of participants whose neonate had an adverse neonatal outcome composite
Defined as one of the following neonatal complications - respiratory distress syndrome, necrotizing enterocolitis, mechanichal ventilation, phototherapy, neonatal intensive care unit admission, sepsis, death
Time frame: Up to 18 weeks
Gestational age
Gestational age at delivery
Time frame: Single evaluation, up to 18 weeks from recruitment
Number of patients who underwent a cesarean delivery
Delivery by cesarean surgery
Time frame: Single evaluation, up to 18 weeks from recruitment
Number of patients who underwent labor induction
Need for labor induction, by mechanichal or pharmaceutical means
Time frame: Single evaluation, up to 18 weeks from recruitment
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