Effects of Glutathione on Immunity in Individuals Training for a Marathon

Inclusion Criteria: * Generally healthy, male or female. * Between the ages of 19-45 years. * Have no medical restrictions and no health conditions that would inhibit participant from marathon run. * Be willing and able to comfortably abstain from any food supplements. * Not participating as a subject in another study. Exclusion Criteria: * BMI \< 20.0 or \> 28.5. * Current or prior use of tobacco products or other inhaled substance. * More than a moderate intake of alcohol (\>1 drink per day in women; \>2 drinks per day in men). * Metabolic or inflammatory disease. * Excellent fitness based on the American College of Sports Medicine criteria for VO2max based on age and gender. * Recent weight loss of \>10 pounds in the last 3-months. * Daily intake of ibuprofen, acetaminophen, aspirin, polyphenol supplements, multivitamins, and/or antioxidant supplements. * Actively attempting (or planning) to lose or gain weight and/or alter body composition. * Currently taking cholesterol-lowering medications. * Currently taking prescription anti-inflammatory medications. * Currently using mouthwash on a regular basis (\>4 times per week). * Orthopedic problems that would limit running capacity. * Currently in very poor or poor fitness. * Highly aerobic exercise trained. * Pregnant or planning to become pregnant during the study period. * Breast feeding * Currently taking blood pressure medications. * Contraindications to strenuous exercise. * Anemic (blood hemoglobin \<10 g/dL and/or hematocrit \<35%). * Diagnosed with asthma or other lung disease.