Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over an 8-week Treatment Period in Adult Subjects With Atopic Dermatitis.

Key Inclusion Criteria: * Age 18 years and above. * Diagnosis of AD as defined by the Hanifin and Rajka 1980 criteria for AD. * History of AD for ≥1 year. * AD involvement of 5-50% treatable body surface area at screening and at baseline (excluding scalp). * Disease severity graded as mild to severe according to vIGA-AD (i.e. vIGA-AD ≥2) at screening and baseline. Key Exclusion Criteria: * AD lesion(s) on scalp at screening and/or baseline. * Active dermatologic conditions that may confound the diagnosis of AD or would interfere with assessment of treatment, such as scabies, cutaneous lymphoma, rosacea, urticaria, or psoriasis. * Known active allergic or irritant contact dermatitis that is likely to interfere with the assessment of severity of AD. * Use of tanning beds or phototherapy within 4 weeks prior to baseline. * Systemic treatment with immunosuppressive/modulating drugs or corticosteroids within 4 weeks prior to baseline or 3 or more bleach baths any week within 4 weeks prior to baseline. * Treatment with topical corticosteroids, topical calcineurin inhibitors, topical phosphodiesterase-4 inhibitors, or oral antibiotics within 2 weeks prior to baseline. * Change in systemic antihistamine therapy within 2 weeks prior to baseline i.e. the subjects must not start antihistamine treatment or change the current dosage regime within 2 weeks prior to baseline. * Receipt of live attenuated vaccines within 4 weeks prior to baseline. * Treatment with any marketed or investigational biologic agents within 6 months or 5 half-lives prior to baseline, or until cell counts return to normal, whichever is longer. * History of any active skin infection within 1 week prior to baseline. * Clinically significant infection (systemic infection or serious skin infection requiring parenteral treatment) within 4 weeks prior to baseline.