Daytime Profile of Salivary Progesterone

Peter Humaidan20 enrolled

Overview

The aim of this study is to perform a 12-hour profile of free saliva progesterone during the luteal phase after fresh and frozen embryo transfer. If progesterone levels in saliva samples show a constant level during daytime, this non-invasive measurement can be used in future ART patients with insufficient progesterone levels who might benefit from additional exogenous progesterone supplementation.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Infertility, Female

Interventions

Progesterone analysis in salivaDIAGNOSTIC_TEST

Analysis of salava progesterone

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18-45 years * One or two good quality embryos for transfer on day 5. * BMI \>18,5 \<30 kg/m² Exclusion Criteria: * No good quality embryos for transfer * Uterine abnormalities * One ovary * Oocyte donation

Locations (1)

Fertility Clinic Regional Hospital Skive

Skive, Denmark

Outcomes

Primary Outcomes

Levels of free progesterone in saliva

Time frame: 12 hours

Secondary Outcomes

Clinical pregnancy rate

Ultrasound detected gestational sack divided with number of embryo transfer

Time frame: 8 weeks

Ongoing pregnancy rate

Viable pregnancy after gestational week 12+0

Time frame: 12 weeks

Data from ClinicalTrials.gov

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