Polysomnographic Findings in Nasal Polyposis

University Hospital, Lille30 enrolled

Overview

Nasal polyposis (NP) is a chronic inflammatory disease of the nasal and sinus mucosa leading to protrusion of edematous polyps in the nasal cavity. Prevalence of NP among the chronic rhinosinusitis patients is 25-30 %. NP leads to significant limitations in physical, emotional and social aspects of life of the affected patients. Sleep disorder is frequently reported by those patients with impaired nasal breathing. Till now few studies have objectively assessed the impact of NP on sleep quality. the objectives are to figure out sleep disturbances in NP and to analyze the outcomes of sinus surgery on sleep recovering.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Chronic Rhinosinusitis With Nasal Polyps Obstructive Sleep Apnea

Interventions

Surgical procedure under general anaesthesia: Consists of the removal of bone boundaries between sinus cavities (ethmoidectomy) with nasal polyps resection in order to retrieve nasal patency and sinus drainage Polysomnographic assessment as routinely applied in clinical practice

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who underwent endoscopic sinus surgery for recalcitrant nasal polyposis (failure of a 4-month corticosteroid medical treatment) Social insured patient * Patient willing to comply with all procedures of the study and its duration * Patient giving consent Exclusion Criteria: * Patients with previous nasal surgery for nasal polyposis * Patients with previous continuous positive airway pressure therapy for obstructive sleep apnea * Non-coverage by the social security scheme * Patient unable to receive informed information * Refusal to sign the consent * Person deprived of the liberty * Person benefiting from a system of legal protection (guardianship…)

Outcomes

Primary Outcomes

Change in Slow-wave sleep duration

Slow-wave sleep duration is measured one month before surgery and 3 months after surgery

Time frame: 1 month before surgery and 3 months postoperatively