Impact of Twice-daily Measurement of Expired CO During Hospitalization on Smoking

University Hospital, Montpellier67 enrolled

Overview

The main objective of this study is to show that the repeated (twice-daily) measurement of expired CO during hospitalization helps reduce smoking.

Smoking in France represents 25 billion euros per year in care, hospitalizations and drugs and 78000 deaths / year are linked to a pathology attributable to this addiction. In addition, active consumption of cigarettes is a destabilizing factor for chronic respiratory diseases. During hospitalization for acute respiratory illness, evaluation of smoking cessation remains declarative. Although stopping advice and possibly nicotine replacement therapy are prescribed, no objective measure of smoking is performed to assess the adequacy of this attitude. This project aims to objectively evaluate smoking during hospitalization by measuring twice daily exhaled CO. The impact of this intervention on the duration of hospitalization and smoking 3m after initial admission will also be evaluated. Tobacco consumption patterns based on reason for hospital admission and background pathology will be highlighted. Secondary objectives include: * To measure the impact of expired CO measurement during hospitalization on the smoking status 1 month and 3 months after initial admission. * To determine smoking patterns during hospitalization according to reason for admission and background pathology. * To measure the effect of iterative CO measurement on the duration of stays. * To measure and compare the quality of life of patients. * To study the variability of expired CO measurements.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Hospitalization Smoking

Interventions

Twice-daily expired carbon monoxide (CO) measurementsOTHER

Patients included in this arm will have expired CO measurements every morning and evening during their initial hospitalization.

Minimal controlOTHER

Patients included in this arm will have one expired CO measurement on the morning just after initial hospital admission and a second expired CO measurement one the morning prior to discharge.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient hospitalized in pneumology for acute respiratory illness or scheduled hospitalization, for a minimum duration of 48h. * Signature of informed consent * Patient able to perform all visits and follow the procedures of the study * Affiliatedor beneficiary of French social security (national health insurance) Exclusion Criteria: * Subject who can not read and / or write French * Expected travel that precludes study completion * Patient in palliative care * Inability to maintain apnea more than 8 seconds * Participation in another clinical trial or administration of an off-label drug within 4 weeks prior to inclusion

Locations (1)

Hôpital Arnaud de Villeneuve - CHU de Montpellier

Montpellier, France

Outcomes

Primary Outcomes

% variation in expired CO

Time frame: Baseline to hospital discharge (expected maximum of 28 days)

Secondary Outcomes

Length of hospital stays

Admission and discharge dates are recorded throughout 3 months of follow-up

Time frame: 3 months

Smoking status (never, former current)

Time frame: Baseline (day 0)

Smoking status (never, former current)

Time frame: 1 month

Smoking status (never, former current)

Time frame: 3 months

Data from ClinicalTrials.gov

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