This study aims to establish if programmed intermittent epidural bolus combined to patient controlled analgesia in labour analgesia will lower the hourly bupivacaine consumption when compared to continuous infusion combined with patient controlled analgesia. The investigators' hypothesis is that the use of programmed intermittent epidural bolus will lower the hourly bupivacaine consumption.
Patients are randomised to receive either a programmed bolus of 6ml each 45 minutes or a continuous infusion of 8ml/h. In each group, they have the possibility to add a PCEA bolus of 6ml every 20min as needed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
200
Programmed intermittent epidural bolus added to patient controlled epidural analgesia
Continuous infusion added to patient controlled epidural analgesia
CHUS
Sherbrooke, Quebec, Canada
RECRUITINGDose of bupivacaine in milligrams per hour
Total dose of bupivacaine in milligrams divided by the total duration of the epidural in hours
Time frame: 1 day
Evaluation of pain
Hourly pain measurement by visual analog scale, 0/10 being no pain and 10/10 being the worst pain imaginable
Time frame: 1 day
Anesthesiologist manual bolus
Total boluses by the anesthesiologist
Time frame: 1 day
PCEA boluses received
PCEA boluses received
Time frame: 1 day
PCEA boluses requested
PCEA boluses requested
Time frame: 1 day
Time lapse before the first PCEA request after the epidural connection
Time lapse before the first PCEA request after the epidural connection
Time frame: 1 day
First stage
Duration of the first stage of labour
Time frame: 1 day
Second stage
Duration of the second stage of labour
Time frame: 1 day
Assisted vaginal delivery
Number of assisted vaginal delivery (vacuum, forceps)
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Time frame: 1 day
Cesarean section
Number of unplanned cesarean section
Time frame: 1 day
Motor blockade
Number of patients with a Bromage score ≥1
Time frame: 1 day
Patient satisfaction
Satisfaction of the analgesia provided by the epidural on a visual analog scale of 0-100, 0/100 being no satisfaction at all and 100/100 being entirely satisfied
Time frame: 1 day