Oral Preoperative Carbohydrate on Early Postoperative Outcome After Cesarean Section

Aswan University Hospital200 enrolled

Overview

Preoperative carbohydrate treatments have been widely adopted as part of enhanced recovery after surgery (ERAS) or fast-track surgery protocols. Although fast-track surgery protocols have been widely investigated and have been shown to be associated with improved postoperative outcomes, some individual constituents of these protocols, including preoperative carbohydrate treatment, have not been subject to such robust analysis.

Carbohydrate (sugar-containing) nutritional supplements have become a routine part of the package of care for people undergoing planned surgical procedures. the investigator wanted to discover whether carbohydrate supplements are a useful part of care packages used by doctors to improve recovery after planned cesarean section.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

200

Conditions

Cesarean Section Complications

Interventions

preoperative carbohydrate loadingDRUG

Patients in the treatment group will receive a carbohydrate beverage (total carbohydrates equal to 12.6g/100 mL: 2.1 g monosaccharide, 10.0 g maltodextrin; 240 mOsm/L) in a dose of 800 mL. Patients will be free to drink the beverage from the evening before the operation and up to 2 hours before the induction of anesthesia

PlaceboDRUG

The control group will receive plain water with the same volume and timing of treatment.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnant women undergoing elective caesarean section * Term gestational age (37+0 to 41+6 weeks) * Singleton gestation Exclusion Criteria: * Women with gestational diabetes and diabetes mellitus * Fetal intrauterine growth restriction * Ante-natally detected congenital anomaly which will require admission to the neonatal nursery * Women who received steroids within the past 7 days prior to delivery * Women who did not complete a gestational diabetes screening test

Locations (1)

Aswan University

Aswān, Egypt

Outcomes

Primary Outcomes

Length of hospital stay

Number of days in the hospital for each participant between the groups.

Time frame: 3 weeks

Secondary Outcomes

number of participants experienced nausea

Number of participants experienced nausea

Time frame: 24 hours postoperative

Change in preoperative well-being assessment from baseline to one hour using the 100 millimeter (mm) visual analogue scale

100 mm visual analogue scales for hunger, thirst, anxiety, fatigue and nausea administered on the morning of surgery prior to morning beverage consumption and 60 minutes after the beverage. All measurements will be assessed using the same scale starting at 0 to 100mm with 0 being the worst and 100 being the best and average being 85.

Time frame: ist 24 hours postoperative

neonatal blood glucose concentration at four and ten hours of age

measure neonatal blood glucose level at four and ten hours of age

Time frame: 24 hours post operative

Neonates with plasma glucose level of less than 45 mg/dL between the groups

First umbilical cord blood sample will be taken for plasma glucose level of less than 45 mg/dL to note hypoglycemia between the groups.

Time frame: ist 24 hours postoperative

Data from ClinicalTrials.gov

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