This is a controlled, randomized, subject-masked, 3x3 crossover, non-dispensing, contralateral study. Twenty subjects will be recruited based on their scores (with their habitual lenses) from the Contact Lens Dry Eye Questionnaire-8 and examined on four occasions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
22
Minims Proxymetacaine hydrochloride Eye Drops
Sodium Chloride Solution
The University of Manchester
Manchester, United Kingdom
Subjective Comfort Scores
Subjects were asked to rate how comfortable each eye was overall using a visual analog scale of 0 to 100 where 0=worse comfort imaginable and 100=best comfort imaginable.
Time frame: 5 and 10 Minutes post-treament
Change in Subjective Comfort Scores From Pre-treatment to Post-treatment
Subjects were asked to rate how comfortable each eye was overall using a visual analog scale of 0 to 100 where 0=worse comfort imaginable and 100=best comfort imaginable. Subjects wore their habitual contacts during the pre-treatment assessment.
Time frame: 14-Hours upon Lens-Insertion (pre-treatment), and 10 Minutes post-treament
Subjective Comfort Score Difference Between Post-treatment and Post-insertion Within Anesthetic
Subjects were asked to rate how comfortable each eye was overall on the scale of 0 to 100 where 0=worse comfort imaginable and 100=best comfort imaginable.
Time frame: Immediately after lens-insertion, 5 and 10 minutes post-treatment
Change in Subjective Comfort Between Ocular Regions at Posttreatment Within Anesthetic
Subjects were asked to rate how comfortable each eye was overall on the scale of 0 to 100 where 0=worse comfort imaginable and 100=best comfort imaginable.
Time frame: 5 and 10 minutes post treatment
Change in Subjective Comfort From Pre-treatment to Post-Treatment Between Ocular Regions
Subjects were asked to rate how comfortable each eye was overall on the scale of 0 to 100 where 0=worse comfort imaginable and 100=best comfort imaginable.
Time frame: 14 hours upon lens-insertion (pre-treatment), 5- and 10- minutes post-treatment
Subjective Comfort Difference Between Post-removal and Preinsertion Within Anesthetic and Cornea
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Subjects were asked to rate how comfortable each eye was overall on the scale of 0 to 100 where 0=worse comfort imaginable and 100=best comfort imaginable.
Time frame: Immediately before lens-insertion (pre-insertion), 30 seconds after lens removal