The Combined effect of Vitamin D3 and Omega-3 supplements on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency.
Nothing is published in the literature about effect of vitamin D3 (VD3) and omega-3 fatty acids (omega-3FA) on serum leptin and glycated hemoglobin ( HbA1C) This study will be conducted to investigate effect of VD3 and omega-3FA alone and with each other on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency. This randomized, controlled clinical trial will be designed to test effects of 50,000 IU VD3 weekly and 1000 mg omega-3FA daily for eight weeks, separately and with each other, on on serum leptin and Glycated hemoglobin (Hb A1C) levels .
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
146
VD3 50000 IU/ week for 8 weeks
omega 3 FA group 300 mg once daily for 8 weeks
50000 IU VD3/week for 8 weeks and 300 mg of omega- 3 FA once daily for 8 weeks
Applied Science University
Amman, Jordan
VD 3
Serum level of 25-hydroxyvitamin D
Time frame: 8 weeks
leptin
serum level of leptin
Time frame: 8 weeks
HbA1C
plasma concentration of HbA1C
Time frame: 8 weeks
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no intervention was given