Sleep Patterns in Children and Adolescents With ADHD

Assiut University84 enrolled

Overview

This study is aimed to find out Sleep profile differences in children and adolescents with and without ADHD,Relationship between sleep profile disturbance and ADHD symptoms, Impact of sleep disturbance on cognition functions and quality of life.

Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder of childhood, affecting 3 -5% children \& adolescent worldwide . Inattention, hyperactivity, and impulsiveness are the major ADHD symptoms based on the diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition . Sleep has been referred to as a "window to the central nervous system", owing to its close associations with many other neurophysiological variables. Children are highly vulnerable to sleep disruptions in early childhood, perhaps due to the complexity of the sleep process and children's reliance on caregivers for achieving and maintaining sleep . The relationship between sleep and ADHD is a complex process and has gained renewed interest since clinicians and researchers observed that sleep-related problems and complaints are relatively common among children with ADHD .Previous studies have shown that About 25-50% of children and adolescents with ADHD have sleep disorders , including nocturnal awakenings, phase delay, increased night time activity and insomnia. Evaluation of sleep problems in child \&adolescent clinical settings is commonly lacking, often unrecognized and go untreated in clinical setting. So, Untreated sleep disturbances and sleep disorders pose significant adverse daytime consequences and place children at considerable risk for poor health outcomes . Sleep disturbances impair a child's cognitive functioning and contribute to problems with school attendance and performance .

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sleep Disorder ADHD Cognitive Change

Interventions

PolysomnographyOTHER

Polysomnography Is considered as the gold standard of sleep assessment. It combines a number of measures of body function during sleep, including measurement of brain activity(electroencephalography),eye movements(electrooculography ),muscle activity (electromyography),heart rhythm(electrocardiography).

Eligibility

Sex: ALLMin age: 6 YearsMax age: 17 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Ages 6-17 years inclusive * males or females * Intelligence Quotient( IQ) \> or equal 80 detected by Wechsler Intelligence Scale for Children . * Willingness to comply with all study requirements Inclusion criteria for ADHD group only: • confirmed newly diagnosed ADHD according to DSM-5 Criteria. (American Psychiatric Association) Exclusion Criteria: * History of chronic/significant medical condition * History or Current prescribed use of any psychotropics, including non-stimulant medications for ADHD. * History or Current substance abuse or dependence. * First degree relative with psychosis or bipolar disorder. Exclusion for the ADHD group only: • Meets criteria for any other psychiatric comorbidity Disorder besides ADHD or Oppositional Defiant Disorder (ODD). Exclusion for the Healthy Control group only: • Meets criteria for any psychiatric Disorders.

Locations (1)

Assiut

Asyut, Egypt

Outcomes

Primary Outcomes

polysomnography to measure total sleep time(minutes) in ADHD patients

Time frame: 1 night

polysomnography to measure sleep efficiency(%) in ADHD patients

Time frame: 1 night

Secondary Outcomes

Assessment of cognitive function in children and adolescents with Attention Deficit Hyperactivity Disorders

Conners' continuous performance test to assess cognitive function

Time frame: 2 hours

Data from ClinicalTrials.gov

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