use seseme oil and corticosteroid topically for two groups
* The enrolled patients will be divided randomly into two groups. * Test group will receive topical sesame oil (3 times /day after eating) for a month. * Control group will receive topical corticosteroid (3 times /day after eating) for a month. * Assessment of the appearance score and severity of pain as well as the clinical parameter outcome will be done at baseline and at the end of two and four weeks and will be recorded in the patients' questionnaires \& by clinical sign score . MDA will be measured at the baseline \& at the end of four weeks after treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
Sesame oil(80 gm NaCMC-20 gmSesame oil)
triamcinolone 140 gm-Na CMC 50 gm
pain intensit measure
measured by visual analogue scale where0 no pain and 10 sever pain
Time frame: 4 weeks
reduction of clinical signs measure
Thongprasom Score 5 = white striae with erosive area = 1 cm2 Score 4 = white striae with erosive area \< 1 cm2 Score 3 = white striae with erosive area \> 1 cm2 Score 2 = white striae with atrophic area \< 1 cm2 Score 1 = mild white striae only Score 0 = no lesion normal
Time frame: 4 weeks
Salivary level of oxidative stress biomarker (MDA)
measured by reaction with thiobarbituric acid (TBA)
Time frame: 4 weeks
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