Repetitive transcranial magnetic stimulation is a non-invasive neuromodulation technique used to treat different neuropsychiatric disorders, such as, depression, neuropathic pain, fibromyalgia and obsessive-compulsive disorder. It is known that the heart rate variability is altered in these conditions. Therefore the focus of this research is to show the influence of rTMS on the Heart Rate Variability.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Repetitive transcranial magnetic stimulation was a technique able to modulate the brain circuit restoring the function.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC/FMUSP)
São Paulo, São Paulo, Brazil
Heart rate variability changes
Changes in heart rate variability measured by Polar V800
Time frame: Three times during the entire study. Following the scheme, Until 1 hour before each session, 15 minutes along the each session and until 1 hour after the end of session
Conditioned Pain Modulation
change in pain units on a scale of 0-100. 0 no pain. 100 = the maximum pain
Time frame: 48 hours before the first session of stimulation
Volume in
Determine if volume cortical regions can serve as biomarkers to predict rTMS treatment response in Healthy volunteers
Time frame: 1 week before the first session of stimulation
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