DCB Compared Stenting in Popliteal Lesions

Inclusion Criteria: * Age 18 years or older * Symptomatic peripheral artery disease: * Moderate or severe claudication (Rutherford category 2 or 3) * Critical limb ischemia (Rutherford category 4 or 5) * Atherosclerotic popliteal artery disease (stenosis \> 50%) * Patients with signed informed consent Exclusion Criteria: * Acute critical limb ischemia * Severe critical limb ischemia (Rutherford category 6) * Involvement of SFA disease with stenosis * Continous total occlusion of all proximal infrapopliteal arteries (origin of the anterior tibial artery or tibioperoneal trunk). * Known hypersensitivity or contraindication to any of the following medications: heparin, aspirin, clopidogrel, or contrast agent * Age \> 80 years * Severe hepatic dysfunction (\> 3 times normal reference values) * Significant leucopenia, neutropenia, thrombocytopenia, anemia, or known bleeding diathesis * LVEF \< 40% or clinically overt congestive heart failure * Pregnant women or women with potential childbearing * Life expectancy \<1 year due to comorbidity * Previous bypass surgery or stenting for the target popliteal artery * Untreated inflow disease of the ipsilateral pelvic or femoropopliteal arteries (more than 50% stenosis or occlusion)