This study is a 8-week, randomized, double-blind, placebo-controlled clinical trial of Silk Peptide for the evaluation of efficacy on immune function enhancement.
This study will evaluate Silk Peptide's efficacy on immune function in healthy volunteers who white blood cells count is in between 4000/㎕ and 8000/㎕ by assessing improvements in certain immune indices (i.e. NK cell activity, IFN-γ, TNF-α, IL-1β, 2, 12, IgG1, IgG2).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Enrollment
110
* Ingredient: Silk Peptide * Type: Yellow granule stick * Storage: Room temperature * Weight: Silk Peptide 9g/day * Directions: with water before breakfast and dinner, 9g/day (4.5g×2times/day) * Duration of use: 8 weeks
* Ingredient: Microcrystalline Cellulose * Type: Yellow granule stick * Storage: Room temperature * Weight: Silk Peptide 0g/day * Directions: with water before breakfast and dinner, 9g/day (4.5g×2times/day) * Duration of use: 8 weeks
Laboratory of Clinical Nutrigenetics/Nutrigenomics, Yonsei University.
Seoul, South Korea
RECRUITINGNK(Natural killer) cell activity
Changes of NK(Natural killer) cell activity were before and after the intervention
Time frame: 0 week, 8 week
IFN-γ
Changes of IFN-γ were before and after the intervention
Time frame: 0 week, 8 week
TNF-α
Changes of TNF-α were before and after the intervention
Time frame: 0 week, 8 week
IL-1β
Changes of IL-1β were before and after the intervention
Time frame: 0 week, 8 week
IL-2
Changes of IL-2 were before and after the intervention
Time frame: 0 week, 8 week
IL-6
Changes of IL-6 were before and after the intervention
Time frame: 0 week, 8 week
IL-12
Changes of IL-12 were before and after the intervention
Time frame: 0 week, 8 week
IgG1
Changes of IgG1 were before and after the intervention
Time frame: 0 week, 8 week
IgG2
Changes of IgG2 were before and after the intervention
Time frame: 0 week, 8 week
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