A Genomic Analysis of Evolution of Epithelia Ovarian Tumors

Lei Li40 enrolled

Overview

Epithelial ovarian carcinomatous and borderline components sometimes appeared in one patient. This study aims to analyze the genomic patterns of the carcinomatous and borderline components in the ovarian epithelial tissues. These tissues will be collected from paraffin section by microdissection to distinguish normal, carcinomatous and borderline tissues.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Epithelial Ovarian Cancer Epithelial Ovarian Tumor of Borderline Malignancy Driving Mutations Progression-free Survival

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * Confirmed primary epithelial ovarian borderline tumor with cancer * Signed an approved informed consents * Feasible for sampling Exclusion Criteria: * Not meeting all of the inclusion criteria

Locations (1)

Lei Li

Beijing, Beijing Municipality, China

RECRUITING

Outcomes

Primary Outcomes

Frequencies of somatic driving mutations

The differences of frequencies of somatic driving mutations will be compared between normal, carcinomatous and borderline tissues.

Time frame: Two years

Secondary Outcomes

Progression-free survival

Progression-free survival between patients with differential expressed multi-omics will be compared.

Time frame: Five years

Central Contacts

Lei Li, M.D.

CONTACT

13911988831 lileigh@163.com

Data from ClinicalTrials.gov

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