Predictive Value of Intraoperative Ventilatory Leak Flow in Prolonged Alveolar Air Leak After Lung Resection Surgery

University Hospital, Montpellier300 enrolled

Overview

After lung resection surgery, patients usually receive a postoperative pleural drain. Prolongated alveolar air leak (PAAL) is a frequent complication after lung surgery (6 to 26% of patients), defined by the European Society of Thoracic Surgeons (ESTS) as a duration of drainage greater than or equal to five days. PAAL is most often due to prolongated bubbling of the drain. Prolonged drainage is a leading cause of prolongated hospital stay, increasing care costs. The risk of prolongated drainage can not be predicted with sufficient accuracy. Existing risk scores for PAAL do not take into account the intraoperative ventilatory leakage (IVL). IVL is a parameter displayed on the ventilator (anaesthetic machine that make the patient breathing during surgical procedure). There is new evidences suggesting that IVL could predict the risk of PAAL after lung resection surgery, but these data have to be supplemented by a well conducted prospective study.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

Pronlongated Alveolar Air Leak (PAAL)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * To be 18 years old or older * To be of French nationality or native from an European country affiliated to the French health care system * To be scheduled for pulmonary resection surgery by videothoracoscopy or thoracotomy in the center of the study Exclusion criteria: * Patient minor, or major under legal protection, or enable to give consent * Refusal or consent withdrawal * No pulmonary resection or no pleural drain at the end of the surgical procedure (decided by the surgical team) * Postoperative pleural fistula

Locations (1)

Outcomes

Primary Outcomes

PAAL after pulmonary resection surgery

End of bubbling is assessed by the nursing team in charge of the patient in accordance with the current practice (no bubbling at forced expiration), and validated by the physician in charge.

Time frame: 5 days after operation

Secondary Outcomes

clinical features

Collection of clinical features to identify risk factors for PAAL

Time frame: up to 28 days after the pulmonary resection surgery