A Dietary Intervention to Modify Breast Milk Content in Obese Lactating Women

Arkansas Children's Hospital Research Institute32 enrolled

Overview

This study is a nutrition research study designed to look at how healthy meals can influence the content of breast milk. Moms will be provided with meals that follow a Mediterranean diet pattern for 4 weeks. The goal of the study is to see if breast milk content changes over the 4 week period. The infants of the moms will also be included in the study to measure any changes in growth.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Effect of Diet on Breast Milk Composition

Interventions

Mediterranean DietOTHER

Participants will be provided with meals that follow a Mediterranean meal plan.

Eligibility

Sex: FEMALEMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ≤4.5 months postpartum * BMI 30 - 50 kg/m2 * ≥ 18 years of age * Singleton pregnancy * Exclusive breastfeeding and plans to exclusively breastfeed for at least 6 months postpartum * Mother has a breast pump * Mother is willing to collect breast milk for a 24 hour period. Exclusion Criteria: * Pre-existing conditions (e.g. diabetes, hypertension, heart disease) * Use of recreational drugs, tobacco, or alcohol * Use of medications or supplements for which breastfeeding is contraindicated * Child has internal metal which may be an NMR safety concern

Locations (1)

Arkansas Children's Nutrition Center

Little Rock, Arkansas, United States

Outcomes

Primary Outcomes

Change in breast milk fat concentration by mid-infrared spectroscopy

The primary aim is to test whether the dietary intervention modifies the breast milk fat concentration of obese mothers.

Time frame: The change in breast milk fat concentration will be assessed by mid-infrared spectroscopy by measuring the concentration before the participants begin the dietary intervention, 2 weeks into the intervention, and at the end of the 4-week intervention.

Data from ClinicalTrials.gov

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