Becoming Children With Perinatal Anoxo-Ischemic Encephalopathy Without Indication of Therapeutic Hypothermia

Hospices Civils de Lyon68 enrolled

Overview

There are 3 levels of severity of anoxo-ischemic encephalopathy (EAI): mild, moderate and severe. Therapeutic hypothermia is beneficial in children with moderate EAI. It is ineffective in severe EAI and may be deleterious if there is no EAI. He continues to question his interest in light EAIs. There are few studies on the becoming of children with a mild anoxic-ischemic encephalopathy and not set hypothermia. The main hypothesis of the study is that term newborns with anoxo-ischemic encephalopathy who did not require therapeutic hypothermia have normal psychomotor development at 2 years.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Anoxic-Ischemic Encephalopathy

Interventions

QuestionaireOTHER

Evaluation of psychomotor development in children with mild EAI without indication of therapeutic hypothermia. Precise analysis of the type (motor, sensory, language, epilepsy) and the severity of sequelae by sending a questionnaire to parents. Investigation of early, clinical and paraclinical prognostic factors of good or bad neurodevelopmental outcome. Evaluation of the height-weight growth and the cranial perimeter

Eligibility

Sex: ALLMin age: 2 YearsMax age: 7 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Full-term children, gestational age\> 36 weeks of amenorrhea * Between the 1st of January 2012 and the 31st of December 2016 * Hospitalized in the neonatal resuscitation department of Croix Rousse in Lyon * Perinatal asphyxia with clinical signs of encephalopathy * Indication of therapeutic hypothermia not retained because EAI mild * Where parents were informed and did not object to participation in the study Exclusion Criteria: * Dysmorphic syndrome * Stroke * Children transferred for other criteria (respiratory distress, heart failure ...)

Outcomes

Primary Outcomes

Existence of abnormalities

Abnormalities researched are : abnormal motor, sensory (auditory or visual), delayed psychomotor acquisition compared to the expected (norms), or epilepsy at 2 years. These anomalies will be collected by sending a questionnaire to the parents.

Time frame: maximum 1 years