Postoperative Complications Following Total Knee Arthroplasty

Ufuk University130 enrolled

Overview

The aim of this study is to investigate the effect of combined spinoepidural and general anesthesia on the incidence of postoperative complications following total knee arthroplasty

Total knee arthroplasty is known to cause complications (pulmonary thromboembolism, acute kidney injury, arryhthmias and infection). The investigators aimed to study the effects of two different anesthesia techniques, i.e. combined spinoepidural anesthesia and general anesthesia on the incidence of postoperative complications such as arrhythmia, pulmonary thrombeoembolism, infection, acute kidney injury and mortality.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

130

Conditions

Arthroplasty, Replacement, Knee

Interventions

General AnesthesiaOTHER

The patients in general anesthesia group will undergo general anesthesia

Regional AnesthesiaOTHER

The patients in Group R will be given combined spinoepidural anesthesia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients scheduled to undergo elective unilateral total knee arthroplasty Exclusion Criteria: * Patient refusal * Scheduled for bilateral or unilateral unicondylar knee arthroplasty * Known history of allergy to drugs used in the study * Severe systemic disease * Morbid obesity (BMI\>30) * History of renal dysfunction

Locations (1)

Ufuk University Dr. Rıdvan Ege Hospital

Ankara, Turkey (Türkiye)

RECRUITING