Spirometry Using Electrical Impedance Tomography

Czech Technical University in Prague22 enrolled

Overview

The main aim of this study is to test spirometry measurements using EIT with a calibration using tidal volume obtained from the simultaneous standard spirometry measurement. Another goal is to compare, based on the calibration, the spirometry parameters obtained from separate measurements using EIT and the standard spirometry using a pneumotachograph. All spirometry measurements will be conducted in accordance with the latest available standards of the American Thoracic Society (ATS) and European Respiratory Society (ERS) from the year 2005, including their emendation from 2017.

Adding the pneumotachograph and antibacterial filter to the respiratory system can lead to increased dead space, flow resistance, and change the respiratory pattern. All of these negative features and reduced patient co-operation affect the measured results and their interpretation. The aim of this study is to test spirometry measurement using EIT and evaluate such spirometry parameters as forced vital capacity (FVC), forced expiratory volume exhaled in the first second of a forced expiration (FEV1) and ratio of FEV1/FVC called Tiffeneau index (TI) based on recalculation using the calibration constant. The study will be conducted using Ergostik (Geratherm, Germany) spirometer and EIT system Pulmovista 500 (Dräger, Germany).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Healthy

Interventions

Spirometric examinations realized using the EITDEVICE

Spirometric examinations will be realized using the EIT alone.

Simultaneous measurement by spirometer and EITDEVICE

Spirometric examinations will be realized using the simultaneous measurement by spirometer and EIT

Eligibility

Sex: ALLMin age: 18 YearsMax age: 28 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy males and females \> 18 years old * Signed informed consent has been obtained Exclusion Criteria: * Pregnancy * Cardiac pacemakers * Electrically active implant * Critical illness * Intrathoracic metal implants * Value of body mass index (BMI)\>50

Locations (1)

Department of Biomedical Technology Faculty of Biomedical Engineering Czech Technical University in Prague

Kladno, Czech Republic, Czechia

Outcomes

Primary Outcomes

FVC

forced vital capacity (L)

Time frame: through study completion, an average of 1 year

FEV1

forced expiratory volume exhaled in the first second of a forced expiration (L)

Time frame: through study completion, an average of 1 year

ratio of FEV1/FVC called Tiffeneau index (-)

Time frame: through study completion, an average of 1 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.