The present study aimed to determine the effect of different interventions on lean body mass maintenance under weight loss conditions in overweight and obese premenopausal women. Three study groups were implemented: (1) Protein supplementation (only) group (2) Protein supplementation and walking intervention (3) Protein supplementation, walking and WB-EMS-application. All protocols were applied for 16 week of intervention. A energy deficit of 500 kcal/d was intended however while group (1) focus consistently on energy restriction (500 kcal/d), in group (2) and (3) a combined physical activity (i.e. walking with a volume representing 250 kcal/d) and energy restriction (250 kcal/d) protocol was applied. Total protein uptake including protein supplementation was calculated to average around 1.2 g/kg body mass per day in groups (1) and 1.5 g/kg body mass/d in group (2) and (3). WB-EMS was applied 1.5x 20 min/week (i.e. each Tuesday and every second Thursday). Primary study endpoint was LBM as determined by Dual Energy x-Ray Absorptiometry.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
30
Protein supplementation 1.2 or 1.5 g/kg body mass/d
Walking with a volume corresponding to 250 kcal/d
WB-EMS application 1.5x 20 min/week
Institute of Medical Physics University of Erlangen-Nurnberg
Erlangen, Germany
Lean body mass
Fat and bone free total body mass in kg
Time frame: changes from baseline to 16 week follow-up
Total Body Fat
Total Body Fat in kg
Time frame: changes from baseline to 16 week follow-up
Total Body Fat Rate
Percent Total Body Fat Rate
Time frame: changes from baseline to 16 week follow-up
Appendicular Skeletal Muscle Mass
Lean Body Mass of the upper and lower limbs in kg
Time frame: changes from baseline to 16 week follow-up
Visceral Body Fat
Total visceral body fat in kg
Time frame: changes from baseline to 16 week follow-up
Trunk fat
Total trunk fat in kg
Time frame: changes from baseline to 16 week follow-up
Metabolic Syndrome Z-Score
Summarized Z-Score that included Z-Scores of blood lipids, lipoproteins, glucose, resting blood pressure and waist circumference. Cut-offs based on the definition of the International Diabetes Federations
Time frame: changes from baseline to 16 week follow-up
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