The purpose of this study is to determine whether contezolid acefosamil is as safe and effective as linezolid in the treatment of adult patients with acute bacterial skin and skin structure infections
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
196
IV and oral contezolid acefosamil given twice a day for 10 to 14 days
IV and oral linezolid given twice a day for 10 to 14 days
MicuRx Site #106
Chula Vista, California, United States
MicuRx Site #103
La Mesa, California, United States
MicuRx Site #102
Long Beach, California, United States
MicuRx Site #104
Stockton, California, United States
Early Clinical Response at the Early Assessment Visit (ITT Population)
Early clinical response assessment based on the electronic case report form (eCRF) data at Early Assessment (48-72 hours after start of study drug) where a successful response (i.e., "responder") was defined as a reduction in primary ABSSSI lesion size ≥20% compared to baseline, and the subject did not receive a non-protocol specified systemic antibacterial agent with activity against Gram-positive organisms for the treatment of ABSSSI and did not die of any cause up to Early Assessment.
Time frame: 48 to 72 hours after the start of study drug
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MicuRx Site #107
Butte, Montana, United States
MicuRx Site #105
Las Vegas, Nevada, United States
MicuRx Site #108
Las Vegas, Nevada, United States