Identification of Microbial Properties Predicting a Worsening Course of Fatty Liver Disease

Inclusion Criteria: * patients with non alcoholic fatty liver disese. * patients who give approval to participate in the study Exclusion Criteria: * liver failure * acute or chronic kidney failure * heart failure ( NYHA 3-4) * active cancer * fatty liver due to non alcoholic etiology. * patients who consume drugs from the estrogen/methotrexate family, or chloroquine. * history of hypothyrodism or cushing. * patients who used TPA in the last 6 months . * pathients with chronic liver disease like A1AT, hemochromatosis, wilson, toxic damage and autoimmunity . * special population like - children, pregnant women and patients who lack the ability to make judgment. * infectious liver disease - viral hepatitis or HIV. * inflammatory bowel disease. * patients who underwent surgery of the gastrointestinal trant.