Low Carb vs Normal Carb in Pregnancy

State University of New York at Buffalo11 enrolled

Overview

The overall purpose of this intervention study is to examine whether low-carbohydrate dietary intervention will prevent the development of gestational diabetes mellitus (GDM) in high-risk pregnant women. The results of this study should help further our understanding of how pregnant women can help prevent gestational diabetes mellitus. We hypothesize that a lower carbohydrate diet will prevent the development of GDM.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Gestational Diabetes

Interventions

100 g carbsOTHER

Participants will be assigned a diet of 100g carbs max for the day

MyPlateOTHER

40-65% of daily intake is from carbohydrates

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 18 - 40 years old * BMI \> 30 and/or history of gestational diabetes mellitus * Currently in first trimester of pregnancy with single fetus (e.g. not twins, triplets, etc.) * Newborns of current participants Exclusion Criteria: * Diabetes (types 1 and 2) * History of major chronic disease or blood clotting disorders (e.g., cancer, heart disease, kidney disease, hypertension) * Known fetal anomaly * History of eating disorders * Current use of medications that affect appetite or insulin secretion/sensitivity (e.g. stimulants) * Current use of illegal substances, antipsychotic or opioid substitution medications, alcohol, or tobacco

Locations (1)

SUNY Buffalo

Buffalo, New York, United States

Outcomes

Primary Outcomes

Birth Outcome Questionnaire

Upon delivery of the baby, a birth outcome questionnaire will be collected which includes questions about the delivery and birth of the baby and a question about gestational diabetes. The answer to gestational diabetes or not will be the measure for the outcome.

Time frame: 24 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.