Inflammatory Targeted Laser Treatment of Knee Osteoarthritis

University of Bergen50 enrolled

Overview

This study is conducted to evaluate the effectiveness of low-level laser therapy (LLLT) as an adjunct to exercise therapy in knee osteoarthritis (KOA).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Knee Osteoarthritis

Interventions

Exercise therapyOTHER

* 5 min. warm up with light exercises for the lower limb prior to strength/endurance exercise therapy. * Strength/endurance exercise therapy including level 1 or 2 per session: Level 1: Pelvic lifts (2x15 rep.), one-legged knee bends (2x10 rep. per leg), hip abductions (2x10 rep. per leg). The participants may progress from level 1 to level 2. Level 2: Pelvic lifts (3x15 rep.), one-legged knee bends (3x10 rep. per leg), hip abductions (2x10 rep. per leg), sideways slide (2x10 rep. per leg), and backwards slide (2x10 rep. per leg). The participants may regress from level 2 to level 1.

LLLTOTHER

\- LLLT (60 mW mean output per probe, 904 nm wavelength) applied to the knee in adherence with the recommendations by World Association for Laser Therapy, in terms of dosage per treatment spot.

Sham LLLTOTHER

Eligibility

Sex: ALLMin age: 50 Years

Medical Language ↔ Plain English

Inclusion criteria: * Any gender * Age ≥ 50 years * Pain on movement ≥ 40 mm Visual Analog Scale * Knee pain for the last ≥ 3 months * KOA verified with the American College of Rheumatology criteria using a history and physical examination, i.e. knee pain and at least three of the following: ≥ 50 years old, ≤ 30 minutes of morning stiffness, crepitus on active range of motion, bony tenderness, bony enlargement, and no palpable warmth of synovia Exclusion criteria: * Knee alloplastic * Total meniscectomy * Intra-articular steroid injection and/or oral steroid treatment within the last six months * Cancer * Rheumatoid arthritis * Severe cognitive deficit * Neurological deficits affecting the knee * Inability to speak and understand English/Norwegian

Locations (1)

University of Bergen

Bergen, Norway

Outcomes

Primary Outcomes

Pain on movement

The participants are asked to rate their pain experienced on movement using an unidimensional visual analogue scale (VAS). "No pain" (0) is written in one end and "worst imaginable pain" (100) is written in the other end of the VAS tool.