Impact of Number of Rank of B-lactam Antibiotics on Emergence on Multidrug Resistant Bacteria

Centre Hospitalier Universitaire de Besancon1,300 enrolled

Overview

This study evaluates the impact of rank of Beta lactam antibiotics on emergence of mutlidrug resistant bacteria colonization in intensive care It's retrospective case controle study. Cases are colonized patient by multidrug resistant bacteria hospitalized in intensive care during the fist hospitalization in intensive care. Temoin are patients with the same characteristics than case but no colonized by multidrug resistant bacteria.

The emergence of multidrug resistant is a wordwide problem. B lactam resistant increase. The antibiotic prescription impact this problem. B lactam antibiotic is prescribed everyday in intensive care unit. The switch of antibiotic is common. Antibiotic classes inclue a lot of rank with different spectum that impact the occurrence of resistant.

Study Type

OBSERVATIONAL

Enrollment

1,300

Conditions

Resistant Infection Antibiotic Resistant Infection Beta Lactam Resistant Bacterial Infection Bacterial Resistance

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * all patient hospitalized more than 48 hours in intensive care unit in Besançon between january 2016 and december 2017 Exclusion Criteria: * patient under guardianship * patient allergic to Beta lactam * colonization with mutidrug resistant the first week of hospitalization in intensive care unit

Impact of Number of Rank of B-lactam Antibiotics on Emergence on Multidrug Resistant Bacteria

Overview

Conditions

Interventions

Eligibility

Outcomes

Primary Outcomes

Central Contacts