1. The course of AVN between Initial diagnosis and total hip replacement (THA) is analysed. The impact of early interventions versus conservative therapy in AVN before THA will be evaluated. 2. The short and long term outcomes of AVN patients undergoing THA with respect to complications, reoperations and quality of life are investigated. Potential risk factors for adverse outcomes will be investigated.
The study is to describe the course of avascular necrosis (AVN) of the femoral head from initial diagnosis and to collect data on treatment options and the further course in these cases. The duration from initial diagnosis of AVN to joint replacement as total hip arthroplasty (THA) will be analysed and the course after joint replacement with potential short- and long-term complications will be evaluated. The impact of THA after AVN on activities of daily living will be assessed by Euroquol 5 Dimensions (EQ-5D-5L) and Hip disability and Osteoarthritis Outcome Score (HOOS) questionnaires.
Study Type
OBSERVATIONAL
questionnaires with respect to outcomes: * Reoperations * Short term complications * Long term complications * EQ-5D (current) * HOOS (current) * disease related change of occupation * use of walking aids * comorbidities * medication
questionnaires to assess course of the disease: * from initial diagnosis of AVN to joint replacement as total hip arthroplasty (THA) * therapeutic interventions
arthroplasty-free interval (time until THA)
time from first diagnosis of AVN to joint replacement = time to event data (in the years between 1999-2006)
Time frame: single time point assessment at baseline
rate of reoperations after THA
reoperation after THA = time to event data (in the years between 2000-2007)
Time frame: single time point assessment at baseline
Hip disability and Osteoarthritis Outcome Score (HOOS)
40 item questionnaire to assess patient-relevant outcomes in five separate subscales (pain, symptoms, activity of daily living, sport and recreation function and hip related quality of life). Scores are: None, Mild, Moderate, Severe, Extreme
Time frame: single time point assessment at baseline
Euroquol 5 Dimensions (EQ-5D-5L)
Five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems.
Time frame: single time point assessment at baseline
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