The purpose of this study is to compare the safety and pharmacokinetic characteristics of combination of amlodipine, olmesartan and rosuvastatin and DWJ1351 in healthy male volunteers
The purpose of this study is to compare the safety and pharmacokinetic characteristics of combination of amlodipine, olmesartan and rosuvastatin and DWJ1351 in healthy male volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
64
DWJ1351(FDC Amlodipine/Olmesartan/Rosuvastatin) X 1 tablet followed by Sevikar(Amlodipine/Olmesartan) X 1 tablet and Crestor(Rosuvastatin) X 1 tablet (after washout period)
Sevikar(Amlodipine/Olmesartan) X 1 tablet and Crestor(Rosuvastatin) X 1 tablet followed by FDC Amlodipine/Olmesartan/Rosuvastatin X 1 tablet (after washout period)
Busan Paik Hospital
Busan, South Korea
AUC
AUC
Time frame: [ Time Frame: 0 - 72 hours ]
Cmax
Cmax
Time frame: [ Time Frame: 0 - 72 hours ]
AUCinf
AUCinf
Time frame: [ Time Frame: 0 - 72 hours ]
Tmax
Tmax
Time frame: [ Time Frame: 0 - 72 hours ]
t1/2β
t1/2β
Time frame: [ Time Frame: 0 - 72 hours ]
CL/F
CL/F
Time frame: [ Time Frame: 0 - 72 hours ]
Vdss/F
Vdss/F
Time frame: [ Time Frame: 0 - 72 hours ]
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